Main Objective: Evaluate alternative biofouling control chemicals and operational strategies to optimize performance across the potable reuse treatment train while maintaining treatment performance and finished-water quality. Supporting objectives include: Identify and assess alternative biofouling control chemicals and operational strategies that can reduce membrane fouling and differential pressure, reduce cleaning frequencies, minimize degradation of ultraviolet transmittance (UVT), and reduce lifecycle cost. Evaluate treatment-train performance impacts, including effects on membrane system performance, membrane lifespan, UVT, and ultraviolet advanced oxidation processes (UV- AOP) performance and energy demand, finished-water quality, and concentrate management. Quantify lifecycle benefits and tradeoffs associated with selected strategies, including energy and chemical consumption, membrane replacement and cleaning frequency, monitoring and reporting requirements, operator safety and chemical handling, environmental considerations, and capital/operating and maintenance costs.